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<?covid-19-tdm?>
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<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">Adv. Drug Alcohol Res.</journal-id>
<journal-title>Advances in Drug and Alcohol Research</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Adv. Drug Alcohol Res.</abbrev-journal-title>
<issn pub-type="epub">2674-0001</issn>
<publisher>
<publisher-name>Frontiers Media S.A.</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="publisher-id">11159</article-id>
<article-id pub-id-type="doi">10.3389/adar.2023.11159</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Health Archive</subject>
<subj-group>
<subject>Original Research</subject>
</subj-group>
</subj-group>
</article-categories>
<title-group>
<article-title>Impacts of COVID-19 on alcohol use among help-seeking adults</article-title>
<alt-title alt-title-type="left-running-head">Srinagesh et al.</alt-title>
<alt-title alt-title-type="right-running-head">
<ext-link ext-link-type="uri" xlink:href="https://doi.org/10.3389/adar.2023.11159">10.3389/adar.2023.11159</ext-link>
</alt-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" corresp="yes">
<name>
<surname>Srinagesh</surname>
<given-names>Aradhana</given-names>
</name>
<xref ref-type="aff" rid="aff1">
<sup>1</sup>
</xref>
<xref ref-type="corresp" rid="c001">&#x2a;</xref>
<uri xlink:href="https://loop.frontiersin.org/people/2066358/overview"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Forthal</surname>
<given-names>Sarah</given-names>
</name>
<xref ref-type="aff" rid="aff2">
<sup>2</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Madden</surname>
<given-names>Sean P.</given-names>
</name>
<xref ref-type="aff" rid="aff3">
<sup>3</sup>
</xref>
<uri xlink:href="https://loop.frontiersin.org/people/2262544/overview"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Stein</surname>
<given-names>L. A. R.</given-names>
</name>
<xref ref-type="aff" rid="aff1">
<sup>1</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Muench</surname>
<given-names>Frederick</given-names>
</name>
<xref ref-type="aff" rid="aff2">
<sup>2</sup>
</xref>
</contrib>
</contrib-group>
<aff id="aff1">
<sup>1</sup>
<institution>Department of Psychology</institution>, <institution>University of Rhode Island</institution>, <addr-line>South Kingston</addr-line>, <addr-line>RI</addr-line>, <country>United States</country>
</aff>
<aff id="aff2">
<sup>2</sup>
<institution>Partnership to End Addiction</institution>, <addr-line>New York</addr-line>, <addr-line>NY</addr-line>, <country>United States</country>
</aff>
<aff id="aff3">
<sup>3</sup>
<institution>Feinstein Institutes for Medical Research</institution>, <institution>Northwell Health</institution>, <addr-line>Manhasset</addr-line>, <addr-line>NY</addr-line>, <country>United States</country>
</aff>
<author-notes>
<fn fn-type="edited-by">
<p>
<bold>Edited by:</bold> <ext-link ext-link-type="uri" xlink:href="https://loop.frontiersin.org/people/26681/overview">Emmanuel Onaivi</ext-link>, William Paterson University, United States</p>
</fn>
<fn fn-type="edited-by">
<p>
<bold>Reviewed by:</bold> <ext-link ext-link-type="uri" xlink:href="https://loop.frontiersin.org/people/269676/overview">Z. Carl Lin</ext-link>, Harvard Medical School, United States</p>
<p>
<ext-link ext-link-type="uri" xlink:href="https://loop.frontiersin.org/people/2253255/overview">Lester Rosario Rodriguez</ext-link>, University of Puerto Rico, Puerto Rico</p>
</fn>
<corresp id="c001">&#x2a;Correspondence: Aradhana Srinagesh, <email>asrinagesh@uri.edu</email>
</corresp>
</author-notes>
<pub-date pub-type="epub">
<day>15</day>
<month>05</month>
<year>2023</year>
</pub-date>
<pub-date pub-type="collection">
<year>2023</year>
</pub-date>
<volume>3</volume>
<elocation-id>11159</elocation-id>
<history>
<date date-type="received">
<day>30</day>
<month>12</month>
<year>2022</year>
</date>
<date date-type="accepted">
<day>02</day>
<month>05</month>
<year>2023</year>
</date>
</history>
<permissions>
<copyright-statement>Copyright &#xa9; 2023 Srinagesh, Forthal, Madden, Stein and Muench.</copyright-statement>
<copyright-year>2023</copyright-year>
<copyright-holder>Srinagesh, Forthal, Madden, Stein and Muench</copyright-holder>
<license xlink:href="http://creativecommons.org/licenses/by/4.0/">
<p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.</p>
</license>
</permissions>
<abstract>
<p>The coronavirus (COVID-19) pandemic has been associated with both increased and decreased alcohol use. Authors explored reasons for increased and decreased alcohol use since the COVID-19 lockdown (March 2020) in a sample of help-seeking adults (HSA) participating in a remote-based alcohol reduction text-messaging intervention in the USA. At the time of recruitment, the HSA in this study were interested in reducing rather than stopping their alcohol consumption. An optional self-report questionnaire was completed by 324 participants (mean age 41.6 &#xb1; 10.2&#xa0;years; 71.5% female; 83.9% White) in February 2021. Survey questions assessed sociodemographic factors, social stressors (quarantine conditions, employment status, changes to daily routine), and drinking patterns. Authors fit two ordinal logistic regression models: one for increased drinking and one for decreased drinking, as functions of the potential predictors and control variables. Most participants (<italic>n</italic> &#x3d; 281; 87.0%) reported drinking more than usual since COVID-19 lockdown began. The most common self-reported reasons for drinking more were increased stress/anxiety (74.7%), boredom (69.4%), and spending more time at home (65.5%) whereas reasons for drinking less were less socializing (33.7%) and worrying about how alcohol would impact the immune system (31.5%). Identifying as female, severity of changes to daily routine, and increased access to alcohol were significantly associated with drinking more than usual. These data suggest that the general consequences of the pandemic in the general population (e.g., boredom) led to greater alcohol use among help-seeking adults attempting to reduce their drinking. Identifying these factors may help create more targeted interventions during public health crises.</p>
</abstract>
<kwd-group>
<kwd>COVID-19</kwd>
<kwd>pandemic</kwd>
<kwd>adult</kwd>
<kwd>alcohol</kwd>
<kwd>moderation</kwd>
</kwd-group>
<contract-num rid="cn001">R01AA025058</contract-num>
<contract-sponsor id="cn001">National Institute on Alcohol Abuse and Alcoholism<named-content content-type="fundref-id">10.13039/100000027</named-content>
</contract-sponsor>
</article-meta>
</front>
<body>
<sec id="s1">
<title>Introduction</title>
<p>Excessive alcohol consumption is associated with various health risks and societal challenges [<xref ref-type="bibr" rid="B1">1</xref>, <xref ref-type="bibr" rid="B2">2</xref>]. The health and economic hardships of the COVID-19 pandemic are comparable to or perhaps greater than those of past natural or environmental disasters [<xref ref-type="bibr" rid="B3">3</xref>, <xref ref-type="bibr" rid="B4">4</xref>]. Previous literature suggests when individuals experience periods of economic or psychological stress, they may consume more alcohol, resulting in increased symptoms of alcohol abuse and dependence [<xref ref-type="bibr" rid="B5">5</xref>&#x2013;<xref ref-type="bibr" rid="B9">9</xref>]. In the winter and spring of 2020, governments across the world declared a state of emergency and took drastic measures (e.g., physical distancing, closing businesses, banning large gatherings, quarantining, etc.) to help mitigate the spread of COVID-19. Past literature would suggest that the contextual changes resulting from the measures taken would suggest an increase in harmful alcohol use. However, the current literature on COVID-19-related drinking patterns remains varied, indicating both increased and decreased alcohol consumption [<xref ref-type="bibr" rid="B10">10</xref>&#x2013;<xref ref-type="bibr" rid="B13">13</xref>], or no changes at all [<xref ref-type="bibr" rid="B1">1</xref>, <xref ref-type="bibr" rid="B14">14</xref>, <xref ref-type="bibr" rid="B15">15</xref>].</p>
<p>Emerging evidence from national and global surveys conducted during the peak of the pandemic (March 2020) shows increased rates of substance use, specifically alcohol use [<xref ref-type="bibr" rid="B16">16</xref>]. Preliminary reports suggest, amid COVID-19, both alcohol sales and consumption have increased [<xref ref-type="bibr" rid="B17">17</xref>, <xref ref-type="bibr" rid="B18">18</xref>], potentially in response to the use of alcohol as a coping mechanism for psychological distress [<xref ref-type="bibr" rid="B18">18</xref>]. For instance, a recently published study on alcohol consumption during the pandemic in the United States (US) showed that Americans drank about 14% more alcohol in 2020, and in a report of national sales of alcohol, online sales increased 262% in 2020, compared to 2019 [<xref ref-type="bibr" rid="B19">19</xref>]. Despite alcohol sales not remaining at these levels, overall data for the week ending on 21 March 2020 indicated that online alcohol sales increased by 234% in the US [<xref ref-type="bibr" rid="B19">19</xref>].</p>
<p>Several factors have been posited about the increase in alcohol volume sales. Specifically, individuals may have been stockpiling due to concern over inaccessibility during the pandemic&#x2019;s early phases, which may have inflated these trends; it is likely that the increase in sales was at least partly related to an increase in consumption. Increased accessibility to alcohol is also a known risk factor for increased alcohol use [<xref ref-type="bibr" rid="B20">20</xref>, <xref ref-type="bibr" rid="B21">21</xref>]. The negative impact of the COVID-19 pandemic on financial health and social functioning may have increased levels of psychological distress, social isolation, income insecurity, lack of work boundaries due to working from home, and job loss, contributing to increased alcohol consumption [<xref ref-type="bibr" rid="B12">12</xref>, <xref ref-type="bibr" rid="B22">22</xref>&#x2013;<xref ref-type="bibr" rid="B29">29</xref>]. Additional factors associated with increased alcohol consumption during the lockdown period included reduced healthcare access, increased access to alcohol delivery services, parental status (i.e., parent versus non-parent), less social connectedness, and increased levels of depression [<xref ref-type="bibr" rid="B28">28</xref>, <xref ref-type="bibr" rid="B30">30</xref>, <xref ref-type="bibr" rid="B31">31</xref>].</p>
<p>Conversely, reduced availability and affordability of alcoholic beverages, lack of social gatherings, whether alcohol was considered an essential item, financial distress, and closure of bars were associated with reduced alcohol consumption [<xref ref-type="bibr" rid="B12">12</xref>, <xref ref-type="bibr" rid="B32">32</xref>&#x2013;<xref ref-type="bibr" rid="B34">34</xref>]. These findings suggest that restrictions limiting access to alcohol, particularly outside the home (e.g., social gatherings, bars, happy hour, and pubs) might have led to lower alcohol use in certain populations. Additionally, one study suggests that alcohol consumption during COVID-19 decreased among men, while it remained steady among women [<xref ref-type="bibr" rid="B35">35</xref>]. This may have been due to broad gender differences in the relationship between loneliness and alcohol use: For instance, feelings of loneliness experienced early in the pandemic were associated with increased alcohol problems for women and a slow decline in alcohol use over time for men. The varying evidence suggests that the relationship between alcohol consumption and COVID-19 is more nuanced, possibly affecting distinct subpopulations in diverse ways. Some variables have been related to both increased and decreased use. For instance, a plausible rationale may be that some individuals were social drinkers, in which case they would decrease their use. On the other hand, some may prefer to drink alone and so their drinking increased.</p>
<p>In the present study, we sought to examine increases and decreases in alcohol use in help-seeking adults (HSA) with at-risk drinking, who may have viewed the pandemic as an opportunity to reduce their drinking and meet their drinking goals. Specifically, the HAS in this study were looking to reduce their drinking via text messaging intervention, rather than through traditional treatment (i.e., Alcoholics Anonymous, in-patient, outpatient).</p>
<p>The National Institute on Alcohol Abuse and Alcoholism (NIAAA) defines at-risk drinking as drinking above the recommended drinking guidelines (i.e., &#x2264;3 standard drinks in one sitting or &#x2264;7 per week for women, and &#x2264;4 standard drinks in one sitting or &#x2264;14 per week for men) without meeting criteria for more severe alcohol use disorders (AUD). At-risk drinkers are at a higher risk of experiencing negative consequences related to drinking along with the risk of progressing to an AUD [<xref ref-type="bibr" rid="B36">36</xref>, <xref ref-type="bibr" rid="B37">37</xref>].</p>
<p>Although research finds that many individuals reported changing their drinking during the pandemic [<xref ref-type="bibr" rid="B33">33</xref>, <xref ref-type="bibr" rid="B38">38</xref>, <xref ref-type="bibr" rid="B39">39</xref>], there are currently no published data on the impacts of COVID-19 on alcohol consumption among individuals who were seeking to reduce their drinking prior to the pandemic. The present study explores potential predictors of changes in drinking among HSA participating in an alcohol reduction text-messaging intervention. As COVID-19 continues to evolve, understanding the immediate and long-term impacts of alcohol consumption among vulnerable populations can inform appropriate clinical and policy interventions.</p>
</sec>
<sec sec-type="materials|methods" id="s2">
<title>Materials and methods</title>
<sec id="s2-1">
<title>Procedure</title>
<p>Participants were recruited from our primary study (Muench et al., under revision), a randomized controlled trial of mobile messaging interventions for HSA with at-risk drinking, which recruited prospective participants primarily via social media outlets such as Facebook or online alcohol screening/help-seeking sources such as <ext-link ext-link-type="uri" xlink:href="http://AlcoholScreening.org">AlcoholScreening.org</ext-link>. This study was approved by both the Feinstein Institutes for Medical Research and Solutions IRB, and clinical investigations were conducted according to the principles expressed in the Declaration of Helsinki. All participants provided electronic informed consent. To meet the eligibility criteria, participants had to consume at least 13 and 15 standard drinks per week for women and men, respectively, which was later modified to include 9 and 11 standard drinks per week for women and men, respectively. Recruitment commenced in March 2019, prior to the pandemic; however, the vast majority of participants enrolled the following year in March 2020, during the pandemic (<italic>n</italic> &#x3d; 671; 92%). For the present study, on 5 February 2021, study staff invited all 731 participants via text message to complete an optional cross-sectional questionnaire about their alcohol use since COVID-19 lockdown began. A total of 403 responses were received. Duplicate entries were discarded (<italic>n</italic> &#x3d; 64; keeping the first or most complete response), as well as blank entries (<italic>n</italic> &#x3d; 3), and data that could not be linked to a trial participant (<italic>n</italic> &#x3d; 12), resulting in a final sample size of 324.</p>
</sec>
<sec id="s2-2">
<title>Measures</title>
<p>The questionnaire (11 questions) was administered via REDCap [<xref ref-type="bibr" rid="B40">40</xref>], a secure web-based application, and assessed lockdown-related effects and behaviors (compliance with social distancing and changes to employment status, fear of contracting COVID-19, and mental health implications, daily routine, and alcohol supply). We assessed changes in drinking since lockdown began through 4 questions in March of 2020. Sociodemographic data (age, sex, race, marital status, and education level) were collected previously when participants enrolled in the primary study. The questionnaire was open for 7&#xa0;days, and a reminder text was sent to complete it on 12 February 2021. Participants did not receive compensation for completing the questionnaire.</p>
<p>Questions assessing the impacts of COVID-19 were adapted from The Pandemic Stress Index [<xref ref-type="bibr" rid="B41">41</xref>], Coronavirus Impact Scale [<xref ref-type="bibr" rid="B42">42</xref>], and COVID-19 Community Response Survey [<xref ref-type="bibr" rid="B43">43</xref>]. The Resource Portal created by NIH was utilized to find COVID-19-specific survey tools [<xref ref-type="bibr" rid="B44">44</xref>].</p>
<p>Compliance with social distancing was assessed by asking: 1) &#x201c;Have you practiced social distancing? (i.e., reduced your physical contact with people outside of your home in social, work, or school settings by avoiding large groups and staying 3&#x2013;6 feet away from other people when out in public)&#x201d; and 2) &#x201c;Do you regularly wear a mask when outside of your house or pod&#x2a;? (&#x2a;a group of people from different households who agree to social distance from other people but not each other).&#x201d;</p>
<p>Self-reported changes in drinking since the COVID-19 lockdown began were assessed with the question: &#x201c;Have you experienced any of the following because of COVID-19 (since COVID-19 lockdown began)?&#x201d; Respondents selected the frequency at which they &#x201c;drank more than usual&#x201d; and &#x201c;drank less than usual&#x201d; (very frequently, frequently, occasionally, rarely, never, or prefer not to say). Responses were coded as ordinal variables ranging from 1 (never) to 5 (very frequently). Respondents who indicated they drank more or less than usual also reported their perceived reasons for doing so. Possible reasons for drinking more were: increased stress/anxiety, boredom, spending more time at home, easily becoming a part of the routine, worrying about COVID-19 and/or the future, enjoying drinking more, working additional hours, being dependent on alcohol, and other sources. Possible reasons for drinking less were: decreased stress/anxiety, less socializing, worrying about how alcohol would impact the immune system, worrying about becoming ill from COVID-19, having diagnosed or suspected COVID-19, working additional hours, having financial concerns, enjoying drinking less, and other. Participants could select multiple reasons and were prompted to &#x201c;select more than one option if it applies.&#x201d; Question and response options were adapted from the survey that Grossman et al. [<xref ref-type="bibr" rid="B24">24</xref>] used in their study. Frequency of alcohol use was also assessed by asking: &#x201c;Since COVID-19 lockdown began, how often did you usually have any kind of drink containing alcohol? By a drink we mean half an ounce of absolute alcohol (e.g., a 12-ounce can or glass of beer or cooler, a 5-ounce glass of wine, or a drink containing 1 shot of liquor). Choose only one.&#x201d; with the following answer choices: every day, 5 to 6 times a week, 3 to 4 times a week, twice a week, once a week, 2 to 3 times a month, once a month, 3 to 11 times in the past year, and 1 or 2 times in the past year.</p>
<p>Potential predictors of changes in drinking included lockdown-related (compliance with social distancing and changes to employment status, daily routine, and alcohol supply) and sociodemographic (age, sex, race, marital status, and education level) variables, all self-reported and categorized as shown in <xref ref-type="table" rid="T1">Table 1</xref>. Authors also included as control variables the number of days each participant had been in the intervention trial, calculated as the difference between their baseline and COVID-19 questionnaire dates, and the type of intervention received as part of the trial.</p>
<table-wrap id="T1" position="float">
<label>TABLE 1</label>
<caption>
<p>Questionnaire responses and their associations with changes in drinking (N &#x3d; 324).</p>
</caption>
<table>
<thead valign="top">
<tr>
<th align="left">Characteristic</th>
<th align="left">Mean (SD)</th>
<th align="left">OR (95% CI), drank more<xref ref-type="table-fn" rid="Tfn1">
<sup>a</sup>
</xref>
</th>
<th align="left">OR (95% CI), drank less<xref ref-type="table-fn" rid="Tfn1">
<sup>a</sup>
</xref>
</th>
</tr>
</thead>
<tbody valign="top">
<tr>
<td align="left">Age (N &#x3d; 308)</td>
<td align="left">41.6 (10.1)</td>
<td align="left">1.00 (0.97, 1.02)</td>
<td align="left">0.98 (0.95, 1.00)</td>
</tr>
</tbody>
</table>
<table>
<thead valign="top">
<tr>
<td align="left"/>
<td align="left">N (%)</td>
<td align="left">OR (95% CI), drank more<xref ref-type="table-fn" rid="Tfn1">
<sup>a</sup>
</xref>
</td>
<td align="left">OR (95% CI), drank less<xref ref-type="table-fn" rid="Tfn1">
<sup>a</sup>
</xref>
</td>
</tr>
</thead>
<tbody valign="top">
<tr>
<td colspan="4" align="left">Sex</td>
</tr>
<tr>
<td align="left">&#x2003;Male</td>
<td align="left">92 (28.4)</td>
<td align="left">REF</td>
<td align="left">REF</td>
</tr>
<tr>
<td align="left">&#x2003;Female</td>
<td align="left">232 (71.6)</td>
<td align="left">1.21 (0.74, 1.98)</td>
<td align="left">0.87 (0.53, 1.43)</td>
</tr>
<tr>
<td colspan="4" align="left">Race</td>
</tr>
<tr>
<td align="left">&#x2003;White</td>
<td align="left">272 (84.0)</td>
<td align="left">REF</td>
<td align="left">REF</td>
</tr>
<tr>
<td align="left">&#x2003;Non-white<xref ref-type="table-fn" rid="Tfn2">
<sup>b</sup>
</xref>
</td>
<td align="left">52 (16.1)</td>
<td align="left">0.56 (0.31, 1.04)</td>
<td align="left">1.28 (0.68, 2.41)</td>
</tr>
<tr>
<td colspan="4" align="left">Marital status</td>
</tr>
<tr>
<td align="left">&#x2003;Single (never married)</td>
<td align="left">86 (26.5)</td>
<td align="left">REF</td>
<td align="left">REF</td>
</tr>
<tr>
<td align="left">&#x2003;Married</td>
<td align="left">159 (49.1)</td>
<td align="left">0.64 (0.37, 1.12)</td>
<td align="left">0.88 (0.51, 1.52)</td>
</tr>
<tr>
<td align="left">&#x2003;Separated, divorced, or widowed</td>
<td align="left">79 (24.4)</td>
<td align="left">0.89 (0.46, 1.73)</td>
<td align="left">0.93 (0.49, 1.79)</td>
</tr>
<tr>
<td colspan="4" align="left">Education level</td>
</tr>
<tr>
<td align="left">&#x2003;Associates degree or less</td>
<td align="left">87 (26.9)</td>
<td align="left">REF</td>
<td align="left">REF</td>
</tr>
<tr>
<td align="left">&#x2003;Bachelor&#x2019;s degree or more</td>
<td align="left">237 (73.2)</td>
<td align="left">1.24 (0.74, 2.10)</td>
<td align="left">0.61 (0.36, 1.03)</td>
</tr>
<tr>
<td colspan="4" align="left">Have you practiced social distancing?</td>
</tr>
<tr>
<td align="left">&#x2003;No, I do not social distance</td>
<td align="left">42 (13.2)</td>
<td align="left">REF</td>
<td align="left">REF</td>
</tr>
<tr>
<td align="left">&#x2003;Yes, I have been completely quarantined (alone or with family)</td>
<td align="left">44 (13.6)</td>
<td align="left">
<bold>0.33 (0.14, 0.82)</bold>
</td>
<td align="left">1.22 (0.51, 2.91)</td>
</tr>
<tr>
<td align="left">&#x2003;Yes, I have seen others indoors but not been within about six feet of individuals outside my household</td>
<td align="left">125 (38.6)</td>
<td align="left">
<bold>0.38 (0.18, 0.79)</bold>
</td>
<td align="left">1.44 (0.70, 2.94)</td>
</tr>
<tr>
<td align="left">&#x2003;Yes, I have seen others outdoors but not been within about six feet of individuals outside my household</td>
<td align="left">112 (34.6)</td>
<td align="left">
<bold>0.29 (0.14, 0.63)</bold>
</td>
<td align="left">1.46 (0.69, 3.07)</td>
</tr>
<tr>
<td colspan="4" align="left">Has your employment status been affected by COVID-19?</td>
</tr>
<tr>
<td align="left">&#x2003;No, I am able to work from home</td>
<td align="left">117 (36.1)</td>
<td align="left">REF</td>
<td align="left">REF</td>
</tr>
<tr>
<td align="left">&#x2003;No, I was not working before</td>
<td align="left">21 (6.5)</td>
<td align="left">1.02 (0.38, 2.76)</td>
<td align="left">0.62 (0.23, 1.67)</td>
</tr>
<tr>
<td align="left">&#x2003;No, I am working same as before</td>
<td align="left">139 (42.9)</td>
<td align="left">0.76 (0.46, 1.25)</td>
<td align="left">0.97 (0.59, 1.59)</td>
</tr>
<tr>
<td align="left">&#x2003;Yes, I am currently unemployed due to COVID</td>
<td align="left">47 (14.5)</td>
<td align="left">0.53 (0.26, 1.10)</td>
<td align="left">
<bold>0.41 (0.20, 0.84)</bold>
</td>
</tr>
<tr>
<td colspan="4" align="left">Have your daily routines changed since COVID lockdown began?</td>
</tr>
<tr>
<td align="left">&#x2003;No, I have had no changes to my routines</td>
<td align="left">11 (3.4)</td>
<td align="left">REF</td>
<td align="left">REF</td>
</tr>
<tr>
<td align="left">&#x2003;Yes, I have had mild changes to a few of my routines</td>
<td align="left">60 (18.5)</td>
<td align="left">1.91 (0.60, 6.09)</td>
<td align="left">1.64 (0.50, 5.43)</td>
</tr>
<tr>
<td align="left">&#x2003;Yes, I have had moderate changes across several of my routines</td>
<td align="left">123 (38.0)</td>
<td align="left">3.67 (1.18, 11.37)</td>
<td align="left">0.94 (0.30, 2.99)</td>
</tr>
<tr>
<td align="left">&#x2003;Yes, I have had severe changes across most or all of my routines</td>
<td align="left">130 (40.1)</td>
<td align="left">7.29 (2.26, 23.50)</td>
<td align="left">0.88 (0.27, 2.88)</td>
</tr>
<tr>
<td colspan="4" align="left">Has your access to alcohol been affected by COVID-19?</td>
</tr>
<tr>
<td align="left">&#x2003;No</td>
<td align="left">166 (51.2)</td>
<td align="left">REF</td>
<td align="left">REF</td>
</tr>
<tr>
<td align="left">&#x2003;Yes, my supply has increased (i.e., due to buying in bulk)</td>
<td align="left">126 (38.9)</td>
<td align="left">
<bold>4.19 (2.54, 6.91)</bold>
</td>
<td align="left">
<bold>0.41 (0.25, 0.67)</bold>
</td>
</tr>
<tr>
<td align="left">&#x2003;Yes, my supply has decreased</td>
<td align="left">32 (10.0)</td>
<td align="left">
<bold>0.15 (0.07, 0.33)</bold>
</td>
<td align="left">
<bold>11.00 (4.85, 25.00)</bold>
</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<fn id="Tfn1">
<label>
<sup>a</sup>
</label>
<p>Estimated using ordinal logistic regression models that included all variables in the table, plus the number of days each participant had been in an intervention trial and type of intervention received.</p>
</fn>
<fn id="Tfn2">
<label>
<sup>b</sup>
</label>
<p>Includes participants who identified as Asian/Pacific Islander, Black/African American, Mixed, Native American, and Other race.</p>
</fn>
<fn>
<p>Bolded values are statistically significant at <italic>p</italic> &#x3c; 0.05.</p>
</fn>
<fn>
<p>SD, standard deviation; OR, odds ratio; CI, confidence interval; REF, reference group.</p>
</fn>
</table-wrap-foot>
</table-wrap>
</sec>
<sec id="s2-3">
<title>Statistical analysis</title>
<p>Questionnaire results were reported using frequencies and percentages for categorical variables and means and standard deviations for continuous variables. To explore independent predictors of changes in drinking since COVID-19 lockdown, authors fit two ordinal logistic regression models: one for increased drinking and one for decreased drinking, as functions of the potential predictors and control variables. Regression coefficients for each potential predictor were exponentiated and presented as odds ratios. Each odds ratio represents the proportional increase in odds of indicating a higher frequency of drinking more or less than usually associated with a one-unit change in the predictor, holding other model variables constant. Missing data was handled using listwise deletion. REDCap version 12.2.10,40) was used for data management and SAS version 9.4 [<xref ref-type="bibr" rid="B45">45</xref>] and Stata version 15 [<xref ref-type="bibr" rid="B46">46</xref>] for data cleaning and analyses.</p>
</sec>
</sec>
<sec sec-type="results" id="s3">
<title>Results</title>
<sec id="s3-1">
<title>Sociodemographic variables</title>
<p>The sample was predominantly female-identifying (71.6%), White (84.0%), and had bachelor&#x2019;s degrees or higher (some graduate school or a graduate degree; 73.2%). Participants&#x2019; average age was 41.6&#xa0;years (SD &#x3d; 10.2; range &#x3d; 21&#x2013;75). Roughly half (49.1%) of participants were currently married, and the remaining reported being single and never married (25.5%), or divorced, separated, or widowed (24.4%).</p>
</sec>
<sec id="s3-2">
<title>COVID-19-related variables</title>
<p>Most participants practiced social distancing (86.8%), remained employed (79.0%, including 36.1% working from home), and experienced changes to their routines (96.6%). Approximately half of the participants (<italic>n</italic> &#x3d; 158) reported changes in their supply of alcohol, with 38.9% having increased access and 10.0% having decreased access (<xref ref-type="table" rid="T1">Table 1</xref>).</p>
<p>Most participants (<italic>n</italic> &#x3d; 281) reported drinking more than usual since the COVID-19 lockdown began (22.2% very frequently, 35.8% frequently, 26.9% occasionally, 10.5% rarely, and 4.6% never). The most common self-reported reasons for drinking more were increased stress/anxiety (74.7%), boredom (69.4%), and spending more time at home (65.5%) (<xref ref-type="fig" rid="F1">Figure 1</xref>). Statistically significant predictors of drinking more than usual were not social distancing, experiencing more severe changes to daily routines, and increased access to alcohol (<xref ref-type="table" rid="T1">Table 1</xref>).</p>
<fig id="F1" position="float">
<label>FIGURE 1</label>
<caption>
<p>Reasons participants drank more than usual during the COVID-19 pandemic (N &#x3d; 281).</p>
</caption>
<graphic xlink:href="adar-03-11159-g001.tif"/>
</fig>
<p>Fewer participants (<italic>n</italic> &#x3d; 89) reported drinking less than usual since COVID-19 lockdown began (3.7% very frequently, 6.5% frequently, 22.8% occasionally, 45.1% rarely, and 21.9% never). The most common self-reported reasons for drinking less were less socializing (33.7%) and worrying about how alcohol would impact the immune system (31.5%) (<xref ref-type="fig" rid="F2">Figure 2</xref>). Additionally, among those who reported drinking less, very few selected working additional hours (3%) and financial concerns (6%) as reasons for lowering their alcohol consumption during COVID-19. Statistically significant predictors of drinking less were continued employment and decreased access to alcohol (<xref ref-type="table" rid="T1">Table 1</xref>).</p>
<fig id="F2" position="float">
<label>FIGURE 2</label>
<caption>
<p>Reasons participants drank less than usual during the COVID-19 pandemic (N &#x3d; 89).</p>
</caption>
<graphic xlink:href="adar-03-11159-g002.tif"/>
</fig>
</sec>
</sec>
<sec sec-type="discussion" id="s4">
<title>Discussion</title>
<p>To our knowledge, this study is the first to assess the impacts of COVID-19 on alcohol consumption in a nationally representative sample of HSA with at-risk drinking. The current study highlighted that female gender, increased self-reported stress, boredom, access to alcohol, and disruption to daily routines may particularly increase susceptibility to elevated alcohol use during a pandemic. Although these factors may heighten the susceptibility to increased alcohol use during social distancing measures (or policies) implemented during a pandemic, these effects are not exclusively the result of a pandemic, these effects are not exclusively the result of a pandemic. These data provide evidence of changes in alcohol use and associated consequences during the COVID-19 pandemic, and suggest that the pandemic has led to greater alcohol use among help-seeking adults attempting to reduce their drinking.</p>
<p>Disasters (i.e., traumatic, natural, or environmental) have often been associated with increases in psychiatric symptoms such as depression and anxiety, and increases in substance use [<xref ref-type="bibr" rid="B47">47</xref>]. These conditions were mirrored during COVID-19, particularly during lockdowns throughout the world, where isolation potentially led to alcohol use and misuse in vulnerable individuals [<xref ref-type="bibr" rid="B48">48</xref>]. Variations in physiological stress and impaired decision-making increase risk of stress-induced alcohol consumption [<xref ref-type="bibr" rid="B48">48</xref>]. The literature on substance use emphasizes the importance of controlling the escalation of alcohol consumption during a crisis and notes two possible scenarios: an increase in consumption due to distress or a decrease in consumption due to the lower accessibility of the substance [<xref ref-type="bibr" rid="B26">26</xref>].</p>
<p>Kilian et al. [<xref ref-type="bibr" rid="B49">49</xref>] meta-analytical findings suggest that alcohol use declined during COVID-19 in the general population but revealed an increase in alcohol use among those with higher drinking levels prior to COVID-19, confirming the results of the current study. Emerging data during the pandemic has shown associations between anxiety, depression, and psychological distress with drinking among college students [<xref ref-type="bibr" rid="B50">50</xref>, <xref ref-type="bibr" rid="B51">51</xref>] and adults globally [<xref ref-type="bibr" rid="B13">13</xref>, <xref ref-type="bibr" rid="B52">52</xref>, <xref ref-type="bibr" rid="B53">53</xref>]. Social isolation, boredom, increased availability, and reduced social support may lead to increased drinking [<xref ref-type="bibr" rid="B24">24</xref>, <xref ref-type="bibr" rid="B28">28</xref>, <xref ref-type="bibr" rid="B51">51</xref>]. Carlyle et al. [<xref ref-type="bibr" rid="B54">54</xref>] findings suggest that certain associates of chance (e.g., anxiety, depression, and resilience) and contextual factors (e.g., loneliness and boredom) contributed to changes in the frequency of use among treatment-seeking individuals during the pandemic. Similarly, among participants who reported drinking more in the present study, some reasons provided by participants were: increased stress/anxiety (65%), boredom, nothing to do at home (60%), spending more time at home (57%), easily became part of my routine&#x2019; (47%) and worried about COVID-19 and/or the future (38%). Efforts to overcome boredom, isolation, and psychological distress during a pandemic (e.g., digital interventions, virtual social events, public health education) may be helpful in reducing alcohol consumption.</p>
<p>Past literature suggests two possible mechanisms to explain changes in alcohol consumption in response to economic and employment factors: the first mechanism suggests any increase in alcohol consumption is related to increased situational or psychological distress (i.e., unemployment or loss of salary) and the second mechanism suggests that any decrease in alcohol consumption may be related to decreases in physical and financial availability of alcohol [<xref ref-type="bibr" rid="B55">55</xref>]. When asked about how their employment status has been affected by COVID-19, the majority of the participants were either working the same as before (43%) or were able to work from home&#x2019; (36%) and only a few were unemployed due to COVID-19 (15%). Further, roughly half (51.2%; 166/324) of the participants reported that their access to alcohol was affected by COVID-19 and 39% reported that their alcohol supply has increased (126/324). Nielsen et al. [<xref ref-type="bibr" rid="B56">56</xref>] suggest two possible causal explanations for higher alcohol consumption among those working from home. First, individuals with higher alcohol consumption may choose to work from home to conceal their alcohol use. Second, working from home may facilitate alcohol use that may otherwise not occur [<xref ref-type="bibr" rid="B56">56</xref>]. This may be attributed to the relatively high socioeconomic status (SES) of our sample (earned a bachelor&#x2019;s degree or higher) and a relatively small sample of those who experienced job loss. The findings suggest that any job loss did not occur, or more specifically, to the extent to which it may have influenced a decrease in alcohol consumption.</p>
<p>Emerging literature suggests that women experienced an increase in drinking during the pandemic [<xref ref-type="bibr" rid="B24">24</xref>, <xref ref-type="bibr" rid="B57">57</xref>, <xref ref-type="bibr" rid="B58">58</xref>]. During the pandemic, high increases were observed among women when compared to men in terms of frequency (17% versus 11%, respectively), days of heavy drinking (41% versus 7% among men), and alcohol-related consequences [<xref ref-type="bibr" rid="B59">59</xref>]. Another study observed increases in heavy-drinking episodes by 41% in women since the COVID-19 lockdown [<xref ref-type="bibr" rid="B60">60</xref>]. Our results suggest that Female identifying individuals (<italic>p</italic> &#x3d; 0.002) were significantly more likely to report drinking more than usual. It is possible that because women are more likely to drink as a result of stress and anxiety than men [<xref ref-type="bibr" rid="B61">61</xref>], the consequences of the pandemic put women at greater risk for increased consumption.</p>
<p>To our knowledge, this is the first study to show that the COVID-19 pandemic led to greater alcohol use among HSA attempting to reduce their drinking versus the general population. More research is needed to examine the contexts of drinking during COVID-19 among problem drinkers. Pandemic-like events are expected to increase in the coming decades [<xref ref-type="bibr" rid="B62">62</xref>]. The implementation of alcohol prevention strategies in the context of health crises, paying particular attention to individuals working from home and focusing on their reasons and motivations in this specific stress-induced alcohol use context, can help to mitigate the harmful effects of excessive alcohol consumption during challenging times. Identifying and addressing these contextual factors can inform alcohol prevention and control strategies during the current pandemic and may also inform risk and prevention strategies in future pandemics.</p>
</sec>
<sec id="s5">
<title>Limitations</title>
<p>This study has several limitations. These findings may not be generalizable to the general population of drinkers due to participants being predominantly female-identifying, White, having bachelor&#x2019;s degrees or higher (some graduate school or a graduate degree) and being help-seeking for alcohol misuse. Considering that the majority of the participants held a bachelor&#x2019;s degree or higher may allow increased flexibility in work arrangements, which may have impacted the differences in alcohol consumption [<xref ref-type="bibr" rid="B63">63</xref>]. Only self-report questions were used to collect drinking and impacts of drinking data, so the data may be under- or over-reported and subjected to social desirability bias. However, self-report of alcohol use and alcohol use-related behaviors is considered to be relatively valid [<xref ref-type="bibr" rid="B64">64</xref>]. Given the cross-sectional design and novelty of the COVID-19 pandemic, the current study limits our ability to make any causal inferences about changes in alcohol consumption prior to and during the pandemic beyond our self-reported question stem &#x201c;since the pandemic began&#x201d; anchoring people. Participants were also enrolled in an alcohol intervention study with different treatment groups that received varying levels of intervention. While no differences existed based on treatment conditions, findings may differ in a sample of individuals who were not participating in a treatment study. Lastly, participants&#x2019; geographic locations were not accounted for, so the differences in COVID-19 lockdown policies and alcohol sale policies (i.e., to-go alcohol, alcohol delivery services, and liquor stores deemed as essential services) may have influenced alcohol consumption. Despite the highlighted limitations, a novel contribution of the findings distinguishes the impacts of COVID-19 on alcohol consumption among individuals seeking to change their drinking prior to the pandemic.</p>
</sec>
</body>
<back>
<sec sec-type="data-availability" id="s6">
<title>Data availability statement</title>
<p>The raw data supporting the conclusion of this article will be made available by the authors, without undue reservation.</p>
</sec>
<sec id="s7">
<title>Ethics statement</title>
<p>The studies involving human participants were reviewed and approved by both the Feinstein Institutes for Medical Research and Solutions IRB and all clinical investigations were conducted according to the principles expressed in the Declaration of Helsinki. The patients/participants provided their written informed consent to participate in this study.</p>
</sec>
<sec id="s8">
<title>Author contributions</title>
<p>AS: Conceptualized and designed survey, collected data, drafted outline, and edited paper. SF: Conducted data analysis, drafted sections of the paper, and edited paper. SM: Helped collect data and provided critical revision of paper. LS: Provided critical revision of paper. FM: Supervised data collection, provided critical revision of paper. All authors contributed to the article and approved the submitted version.</p>
</sec>
<sec id="s9">
<title>Funding</title>
<p>This work was supported by the National Institute on Alcohol Abuse and Alcoholism under grant number R01AA025058 (PI: Muench).</p>
</sec>
<sec sec-type="COI-statement" id="s10">
<title>Conflict of interest</title>
<p>The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.</p>
</sec>
<ack>
<p>Authors wish to acknowledge Cameron Haslip and Sherry Oommen for their support of the project. Authors also thank Dr. Amy L. Stamates for helpful feedback on previous versions of this manuscript and Dawa Sherpa and Harold D. Montilla for editorial assistance. Most importantly, authors would like to gratefully acknowledge the study participants.</p>
</ack>
<ref-list>
<title>References</title>
<ref id="B1">
<label>1.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Manthey</surname>
<given-names>J</given-names>
</name>
<name>
<surname>Kilian</surname>
<given-names>C</given-names>
</name>
<name>
<surname>Carr</surname>
<given-names>S</given-names>
</name>
<name>
<surname>Bart&#xe1;k</surname>
<given-names>M</given-names>
</name>
<name>
<surname>Bloomfield</surname>
<given-names>K</given-names>
</name>
<name>
<surname>Braddick</surname>
<given-names>F</given-names>
</name>
<etal/>
</person-group> <article-title>Use of Alcohol, Tobacco, Cannabis, and Other Substances during the First Wave of the SARS-CoV-2 Pandemic in Europe: A Survey on 36,000 European Substance Users</article-title>. <source>Subst Abuse Treat Prev Pol</source> (<year>2021</year>) <volume>16</volume>:<fpage>36</fpage>. <pub-id pub-id-type="doi">10.1186/s13011-021-00373-y</pub-id>
</citation>
</ref>
<ref id="B2">
<label>2.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Murray</surname>
<given-names>CJ</given-names>
</name>
<name>
<surname>Aravkin</surname>
<given-names>AY</given-names>
</name>
<name>
<surname>Zheng</surname>
<given-names>P</given-names>
</name>
<name>
<surname>Abbafati</surname>
<given-names>C</given-names>
</name>
<name>
<surname>Abbas</surname>
<given-names>KM</given-names>
</name>
<name>
<surname>Abbasi-Kangevari</surname>
<given-names>M</given-names>
</name>
<etal/>
</person-group> <article-title>Global burden of 87 Risk Factors in 204 Countries and Territories, 1990&#x2013;2019: a Systematic Analysis for the Global Burden of Disease Study 2019</article-title>. <source>The Lancet</source> (<year>2020</year>) <volume>396</volume>(<issue>10258</issue>):<fpage>1223</fpage>&#x2013;<lpage>49</lpage>. <pub-id pub-id-type="doi">10.1016/S0140-6736(20)30752-2</pub-id>
</citation>
</ref>
<ref id="B3">
<label>3.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Mofijur</surname>
<given-names>M</given-names>
</name>
<name>
<surname>Fattah</surname>
<given-names>IMR</given-names>
</name>
<name>
<surname>Alam</surname>
<given-names>MA</given-names>
</name>
<name>
<surname>Islam</surname>
<given-names>ABMS</given-names>
</name>
<name>
<surname>Ong</surname>
<given-names>HC</given-names>
</name>
<name>
<surname>Rahman</surname>
<given-names>SMA</given-names>
</name>
<etal/>
</person-group> <article-title>Impact of COVID-19 on the Social, Economic, Environmental and Energy Domains: Lessons Learnt from a Global Pandemic</article-title>. <source>Sustain Prod Consum</source> (<year>2021</year>) <volume>26</volume>:<fpage>343</fpage>&#x2013;<lpage>59</lpage>. <pub-id pub-id-type="doi">10.1016/j.spc.2020.10.016</pub-id>
</citation>
</ref>
<ref id="B4">
<label>4.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Shang</surname>
<given-names>Y</given-names>
</name>
<name>
<surname>Li</surname>
<given-names>H</given-names>
</name>
<name>
<surname>Zhang</surname>
<given-names>R</given-names>
</name>
</person-group>. <article-title>Effects of Pandemic Outbreak on Economies: Evidence from Business History Context</article-title>. <source>Front Public Health</source> (<year>2021</year>) <volume>9</volume>:<fpage>632043</fpage>. <pub-id pub-id-type="doi">10.3389/fpubh.2021.632043</pub-id>
</citation>
</ref>
<ref id="B5">
<label>5.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Boscarino</surname>
<given-names>JA</given-names>
</name>
<name>
<surname>Kirchner</surname>
<given-names>HL</given-names>
</name>
<name>
<surname>Hoffman</surname>
<given-names>SN</given-names>
</name>
<name>
<surname>Sarorius</surname>
<given-names>J</given-names>
</name>
<name>
<surname>Adams</surname>
<given-names>RE</given-names>
</name>
</person-group>. <article-title>PTSD and Alcohol Use after the World Trade Center Attacks: A Longitudinal Study</article-title>. <source>J Trauma Stress</source> (<year>2011</year>) <volume>24</volume>:<fpage>515</fpage>&#x2013;<lpage>25</lpage>. <pub-id pub-id-type="doi">10.1002/jts.20673</pub-id>
</citation>
</ref>
<ref id="B6">
<label>6.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Clay</surname>
<given-names>JM</given-names>
</name>
<name>
<surname>Parker</surname>
<given-names>MO</given-names>
</name>
</person-group>. <article-title>The Role of Stress-Reactivity, Stress-Recovery and Risky Decision-Making in Psychosocial Stress-Induced Alcohol Consumption in Social Drinkers</article-title>. <source>Psychopharmacology</source> (<year>2018</year>) <volume>235</volume>(<issue>11</issue>):<fpage>3243</fpage>&#x2013;<lpage>57</lpage>. <pub-id pub-id-type="doi">10.1007/s00213-018-5027-0</pub-id>
</citation>
</ref>
<ref id="B7">
<label>7.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Hasin</surname>
<given-names>DS</given-names>
</name>
<name>
<surname>Sarvet</surname>
<given-names>AL</given-names>
</name>
<name>
<surname>Meyers</surname>
<given-names>JL</given-names>
</name>
<name>
<surname>Saha</surname>
<given-names>TD</given-names>
</name>
<name>
<surname>Ruan</surname>
<given-names>WJ</given-names>
</name>
<name>
<surname>Stohl</surname>
<given-names>M</given-names>
</name>
<etal/>
</person-group> <article-title>Epidemiology of Adult DSM-5 Major Depressive Disorder and its Specifiers in the United States</article-title>. <source>JAMA Psychiatry</source> (<year>2018</year>) <volume>75</volume>(<issue>4</issue>):<fpage>336</fpage>&#x2013;<lpage>46</lpage>. <pub-id pub-id-type="doi">10.1001/jamapsychiatry.2017.4602</pub-id>
</citation>
</ref>
<ref id="B8">
<label>8.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Keyes</surname>
<given-names>KM</given-names>
</name>
<name>
<surname>Hatzenbuehler</surname>
<given-names>ML</given-names>
</name>
<name>
<surname>Grant</surname>
<given-names>BF</given-names>
</name>
<name>
<surname>Hasin</surname>
<given-names>DS</given-names>
</name>
</person-group>. <article-title>Stress and Alcohol: Epidemiologic Evidence</article-title>. <source>Alcohol Res</source> (<year>2012</year>) <volume>34</volume>(<issue>4</issue>):<fpage>391</fpage>&#x2013;<lpage>400</lpage>.</citation>
</ref>
<ref id="B9">
<label>9.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Wu</surname>
<given-names>P</given-names>
</name>
<name>
<surname>Liu</surname>
<given-names>X</given-names>
</name>
<name>
<surname>Fang</surname>
<given-names>Y</given-names>
</name>
<name>
<surname>Fan</surname>
<given-names>B</given-names>
</name>
<name>
<surname>Fuller</surname>
<given-names>CJ</given-names>
</name>
<name>
<surname>Guan</surname>
<given-names>Z</given-names>
</name>
<etal/>
</person-group> <article-title>Alcohol Abuse/dependence Symptoms Among Hospital Employees Exposed to a SARS Outbreak</article-title>. <source>Alcohol Alcohol</source> (<year>2008</year>) <volume>43</volume>(<issue>6</issue>):<fpage>706</fpage>&#x2013;<lpage>12</lpage>. <pub-id pub-id-type="doi">10.1093/alcalc/agn073</pub-id>
</citation>
</ref>
<ref id="B10">
<label>10.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Avery</surname>
<given-names>AR</given-names>
</name>
<name>
<surname>Tsang</surname>
<given-names>S</given-names>
</name>
<name>
<surname>Seto</surname>
<given-names>EY</given-names>
</name>
<name>
<surname>Duncan</surname>
<given-names>GE</given-names>
</name>
</person-group>. <article-title>Stress, Anxiety, and Change in Alcohol Use during the COVID-19 Pandemic: Findings Among Adult Twin Pairs</article-title>. <source>Front Psychiatry</source> (<year>2020</year>) <volume>11</volume>:<fpage>571084</fpage>. <pub-id pub-id-type="doi">10.3389/fpsyt.2020.571084</pub-id>
</citation>
</ref>
<ref id="B11">
<label>11.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Holmes</surname>
<given-names>EA</given-names>
</name>
<name>
<surname>O&#x27;Connor</surname>
<given-names>RC</given-names>
</name>
<name>
<surname>Perry</surname>
<given-names>VH</given-names>
</name>
<name>
<surname>Tracey</surname>
<given-names>I</given-names>
</name>
<name>
<surname>Wessely</surname>
<given-names>S</given-names>
</name>
<name>
<surname>Arseneault</surname>
<given-names>L</given-names>
</name>
<etal/>
</person-group> <article-title>Multidisciplinary Research Priorities for the COVID-19 Pandemic: a Call for Action for Mental Health Science</article-title>. <source>The Lancet Psychiatry</source> (<year>2020</year>) <volume>7</volume>(<issue>6</issue>):<fpage>547</fpage>&#x2013;<lpage>60</lpage>. <pub-id pub-id-type="doi">10.1016/S2215-0366(20)30168-1</pub-id>
</citation>
</ref>
<ref id="B12">
<label>12.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Jackson</surname>
<given-names>KM</given-names>
</name>
<name>
<surname>Merrill</surname>
<given-names>JE</given-names>
</name>
<name>
<surname>Stevens</surname>
<given-names>AK</given-names>
</name>
<name>
<surname>Hayes</surname>
<given-names>KL</given-names>
</name>
<name>
<surname>White</surname>
<given-names>HR</given-names>
</name>
</person-group>. <article-title>Changes in Alcohol Use and Drinking Context Due to the COVID&#x2010;19 Pandemic: a Multimethod Study of College Student Drinkers</article-title>. <source>Alcohol Clin Exp Res</source> (<year>2021</year>) <volume>45</volume>(<issue>4</issue>):<fpage>752</fpage>&#x2013;<lpage>64</lpage>. <pub-id pub-id-type="doi">10.1111/acer.14574</pub-id>
</citation>
</ref>
<ref id="B13">
<label>13.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Rolland</surname>
<given-names>B</given-names>
</name>
<name>
<surname>Haesebaert</surname>
<given-names>F</given-names>
</name>
<name>
<surname>Zante</surname>
<given-names>E</given-names>
</name>
<name>
<surname>Benyamina</surname>
<given-names>A</given-names>
</name>
<name>
<surname>Haesebaert</surname>
<given-names>J</given-names>
</name>
<name>
<surname>Franck</surname>
<given-names>N</given-names>
</name>
</person-group>. <article-title>Global Changes and Factors of Increase in Caloric/salty Food Intake, Screen Use, and Substance Use during the Early COVID-19 Containment Phase in the General Population in France: Survey Study</article-title>. <source>JMIR Public Health Surveill</source> (<year>2020</year>) <volume>6</volume>(<issue>3</issue>):<fpage>e19630</fpage>. <pub-id pub-id-type="doi">10.2196/19630</pub-id>
</citation>
</ref>
<ref id="B14">
<label>14.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Gavurova</surname>
<given-names>B</given-names>
</name>
<name>
<surname>Khouri</surname>
<given-names>S</given-names>
</name>
<name>
<surname>Ivankova</surname>
<given-names>V</given-names>
</name>
<name>
<surname>Kubak</surname>
<given-names>M</given-names>
</name>
</person-group>. <article-title>Changes in Alcohol Consumption and Determinants of Excessive Drinking during the COVID-19 Lockdown in the Slovak Republic</article-title>. <source>Front Public Health</source> (<year>2022</year>) <volume>9</volume>:<fpage>791077</fpage>. <pub-id pub-id-type="doi">10.3389/fpubh.2021.791077</pub-id>
</citation>
</ref>
<ref id="B15">
<label>15.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Sidor</surname>
<given-names>A</given-names>
</name>
<name>
<surname>Rzymski</surname>
<given-names>P</given-names>
</name>
</person-group>. <article-title>Dietary Choices and Habits during COVID-19 Lockdown: Experience from Poland</article-title>. <source>Nutrients</source> (<year>2020</year>) <volume>12</volume>:<fpage>1657</fpage>. <pub-id pub-id-type="doi">10.3390/nu12061657</pub-id>
</citation>
</ref>
<ref id="B16">
<label>16.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Schmidt</surname>
<given-names>RA</given-names>
</name>
<name>
<surname>Genois</surname>
<given-names>R</given-names>
</name>
<name>
<surname>Jin</surname>
<given-names>J</given-names>
</name>
<name>
<surname>Vigo</surname>
<given-names>D</given-names>
</name>
<name>
<surname>Rehm</surname>
<given-names>J</given-names>
</name>
<name>
<surname>Rush</surname>
<given-names>B</given-names>
</name>
</person-group>. <article-title>The Early Impact of COVID-19 on the Incidence, Prevalence, and Severity of Alcohol Use and Other Drugs: A Systematic Review</article-title>. <source>Drug Alcohol Depend</source> (<year>2021</year>) <volume>228</volume>:<fpage>109065</fpage>. <pub-id pub-id-type="doi">10.1016/j.drugalcdep.2021.109065</pub-id>
</citation>
</ref>
<ref id="B17">
<label>17.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Koopmann</surname>
<given-names>A</given-names>
</name>
<name>
<surname>Georgiadou</surname>
<given-names>E</given-names>
</name>
<name>
<surname>Kiefer</surname>
<given-names>F</given-names>
</name>
<name>
<surname>Hillemacher</surname>
<given-names>T</given-names>
</name>
</person-group>. <article-title>Did the General Population in Germany Drink More Alcohol during the COVID-19 Pandemic Lockdown?</article-title> <source>Alcohol Alcohol</source> (<year>2020</year>) <volume>55</volume>(<issue>6</issue>):<fpage>698</fpage>&#x2013;<lpage>9</lpage>. <pub-id pub-id-type="doi">10.1093/alcalc/agaa058</pub-id>
</citation>
</ref>
<ref id="B18">
<label>18.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Chick</surname>
<given-names>J</given-names>
</name>
</person-group>. <article-title>Alcohol and COVID-19</article-title>. <source>Alcohol Alcohol</source> (<year>2020</year>) <volume>55</volume>(<issue>4</issue>):<fpage>341</fpage>&#x2013;<lpage>2</lpage>. <pub-id pub-id-type="doi">10.1093/alcalc/agaa039</pub-id>
</citation>
</ref>
<ref id="B19">
<label>19.</label>
<citation citation-type="book">
<collab>The Nielsen Company</collab>. <source>Rebalancing the &#x2018;COVID-19 Effect&#x2019; on Alcohol Sales</source> (<year>2020</year>). <comment>Available at: <ext-link ext-link-type="uri" xlink:href="https://www.nielsen.com/us/en/insights/article/2020/rebalancing-the-covid-19-effect-on-alcohol-sales/">https://www.nielsen.com/us/en/insights/article/2020/rebalancing-the-covid-19-effect-on-alcohol-sales/</ext-link>
</comment>(<comment>Accessed October 21, 2022)</comment>.</citation>
</ref>
<ref id="B20">
<label>20.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Gruenewald</surname>
<given-names>PJ</given-names>
</name>
<name>
<surname>Johnson</surname>
<given-names>FW</given-names>
</name>
<name>
<surname>Treno</surname>
<given-names>AJ</given-names>
</name>
</person-group>. <article-title>Outlets, Drinking and Driving: a Multilevel Analysis of Availability</article-title>. <source>J Stud Alcohol</source> (<year>2002</year>) <volume>63</volume>(<issue>4</issue>):<fpage>460</fpage>&#x2013;<lpage>8</lpage>. <pub-id pub-id-type="doi">10.15288/jsa.2002.63.460</pub-id>
</citation>
</ref>
<ref id="B21">
<label>21.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>van Oers</surname>
<given-names>JA</given-names>
</name>
<name>
<surname>Garretsen</surname>
<given-names>HF</given-names>
</name>
</person-group>. <article-title>The Geographic Relationship between Alcohol Use, Bars, Liquor Shops and Traffic Injuries in Rotterdam</article-title>. <source>J Stud Alcohol</source> (<year>1993</year>) <volume>54</volume>(<issue>6</issue>):<fpage>739</fpage>&#x2013;<lpage>44</lpage>. <pub-id pub-id-type="doi">10.15288/jsa.1993.54.739</pub-id>
</citation>
</ref>
<ref id="B22">
<label>22.</label>
<citation citation-type="book">
<person-group person-group-type="author">
<name>
<surname>Biddle</surname>
<given-names>N</given-names>
</name>
<name>
<surname>Edwards</surname>
<given-names>B</given-names>
</name>
<name>
<surname>Gray</surname>
<given-names>M</given-names>
</name>
<name>
<surname>Sollis</surname>
<given-names>K</given-names>
</name>
</person-group>. <source>Alcohol Consumption during the COVID-19 Period: May 2020</source> (<year>2020</year>). <comment>Available at:</comment> https://csrm.cass.anu.edu.au/research/publications/alcohol-consumption-during-covid-19-period-may-2020 (<comment>Accessed October 21, 2022)</comment>.</citation>
</ref>
<ref id="B23">
<label>23.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Campbell</surname>
<given-names>AM</given-names>
</name>
</person-group>. <article-title>An Increasing Risk of Family Violence during the Covid-19 Pandemic: Strengthening Community Collaborations to Save Lives</article-title>. <source>Forensic Sci Int Rep</source> (<year>2020</year>) <volume>2</volume>:<fpage>100089</fpage>. <pub-id pub-id-type="doi">10.1016/j.fsir.2020.100089</pub-id>
</citation>
</ref>
<ref id="B24">
<label>24.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Grossman</surname>
<given-names>ER</given-names>
</name>
<name>
<surname>Benjamin-Neelon</surname>
<given-names>SE</given-names>
</name>
<name>
<surname>Sonnenschein</surname>
<given-names>S</given-names>
</name>
</person-group>. <article-title>Alcohol Consumption during the COVID-19 Pandemic: A Cross-Sectional Survey of US Adults</article-title>. <source>Int J Environ Res Public Health</source> (<year>2020</year>) <volume>17</volume>(<issue>24</issue>):<fpage>9189</fpage>. <pub-id pub-id-type="doi">10.3390/ijerph17249189</pub-id>
</citation>
</ref>
<ref id="B25">
<label>25.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Killgore</surname>
<given-names>WD</given-names>
</name>
<name>
<surname>Cloonan</surname>
<given-names>SA</given-names>
</name>
<name>
<surname>Taylor</surname>
<given-names>EC</given-names>
</name>
<name>
<surname>Lucas</surname>
<given-names>DA</given-names>
</name>
<name>
<surname>Dailey</surname>
<given-names>NS</given-names>
</name>
</person-group>. <article-title>Alcohol Dependence during COVID-19 Lockdowns</article-title>. <source>Psychiatry Res</source> (<year>2021</year>) <volume>296</volume>:<fpage>113676</fpage>. <pub-id pub-id-type="doi">10.1016/j.psychres.2020.113676</pub-id>
</citation>
</ref>
<ref id="B26">
<label>26.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Rehm</surname>
<given-names>J</given-names>
</name>
<name>
<surname>Kilian</surname>
<given-names>C</given-names>
</name>
<name>
<surname>Ferreira-Borges</surname>
<given-names>C</given-names>
</name>
<name>
<surname>Jernigan</surname>
<given-names>D</given-names>
</name>
<name>
<surname>Monteiro</surname>
<given-names>M</given-names>
</name>
<name>
<surname>Parry</surname>
<given-names>CDH</given-names>
</name>
<etal/>
</person-group> <article-title>Alcohol Use in Times of the COVID 19: Implications for Monitoring and Policy</article-title>. <source>Drug Alcohol Rev</source> (<year>2020</year>) <volume>39</volume>(<issue>4</issue>):<fpage>301</fpage>&#x2013;<lpage>4</lpage>. <pub-id pub-id-type="doi">10.1111/dar.13074</pub-id>
</citation>
</ref>
<ref id="B27">
<label>27.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Vanderbruggen</surname>
<given-names>N</given-names>
</name>
<name>
<surname>Matthys</surname>
<given-names>F</given-names>
</name>
<name>
<surname>Van Laere</surname>
<given-names>S</given-names>
</name>
<name>
<surname>Zeeuws</surname>
<given-names>D</given-names>
</name>
<name>
<surname>Santermans</surname>
<given-names>L</given-names>
</name>
<name>
<surname>Van den Ameele</surname>
<given-names>S</given-names>
</name>
<etal/>
</person-group> <article-title>Self-reported Alcohol, Tobacco, and Cannabis Use during COVID-19 Lockdown Measures: Results from a Web-Based Survey</article-title>. <source>Eur Addict Res</source> (<year>2020</year>) <volume>26</volume>:<fpage>309</fpage>&#x2013;<lpage>15</lpage>. <pub-id pub-id-type="doi">10.1159/000510822</pub-id>
</citation>
</ref>
<ref id="B28">
<label>28.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Wardell</surname>
<given-names>JD</given-names>
</name>
<name>
<surname>Kempe</surname>
<given-names>T</given-names>
</name>
<name>
<surname>Rapinda</surname>
<given-names>KK</given-names>
</name>
<name>
<surname>Single</surname>
<given-names>A</given-names>
</name>
<name>
<surname>Bilevicius</surname>
<given-names>E</given-names>
</name>
<name>
<surname>Frohlich</surname>
<given-names>JR</given-names>
</name>
<etal/>
</person-group> <article-title>Drinking to Cope during COVID&#x2010;19 Pandemic: The Role of External and Internal Factors in Coping Motive Pathways to Alcohol Use, Solitary Drinking, and Alcohol Problems</article-title>. <source>Alcohol Clin Exp Res</source> (<year>2020</year>) <volume>44</volume>(<issue>10</issue>):<fpage>2073</fpage>&#x2013;<lpage>83</lpage>. <pub-id pub-id-type="doi">10.1111/acer.14425</pub-id>
</citation>
</ref>
<ref id="B29">
<label>29.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Weerakoon</surname>
<given-names>SM</given-names>
</name>
<name>
<surname>Jetelina</surname>
<given-names>KK</given-names>
</name>
<name>
<surname>Knell</surname>
<given-names>G</given-names>
</name>
<name>
<surname>Messiah</surname>
<given-names>SE</given-names>
</name>
</person-group>. <article-title>COVID-19 Related Employment Change Is Associated with Increased Alcohol Consumption during the Pandemic</article-title>. <source>Am J Drug Alcohol Abuse</source> (<year>2021</year>) <volume>47</volume>(<issue>6</issue>):<fpage>730</fpage>&#x2013;<lpage>6</lpage>. <pub-id pub-id-type="doi">10.1080/00952990.2021.1912063</pub-id>
</citation>
</ref>
<ref id="B30">
<label>30.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Huckle</surname>
<given-names>T</given-names>
</name>
<name>
<surname>Parker</surname>
<given-names>K</given-names>
</name>
<name>
<surname>Romeo</surname>
<given-names>JS</given-names>
</name>
<name>
<surname>Casswell</surname>
<given-names>S</given-names>
</name>
</person-group>. <article-title>Online Alcohol Delivery Is Associated with Heavier Drinking during the First New Zealand COVID&#x2010;19 Pandemic Restrictions</article-title>. <source>Drug alcohol Rev</source> (<year>2021</year>) <volume>40</volume>(<issue>5</issue>):<fpage>826</fpage>&#x2013;<lpage>34</lpage>. <pub-id pub-id-type="doi">10.1111/dar.13222</pub-id>
</citation>
</ref>
<ref id="B31">
<label>31.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>McPhee</surname>
<given-names>MD</given-names>
</name>
<name>
<surname>Keough</surname>
<given-names>MT</given-names>
</name>
<name>
<surname>Rundle</surname>
<given-names>S</given-names>
</name>
<name>
<surname>Heath</surname>
<given-names>LM</given-names>
</name>
<name>
<surname>Wardell</surname>
<given-names>JD</given-names>
</name>
<name>
<surname>Hendershot</surname>
<given-names>CS</given-names>
</name>
</person-group>. <article-title>Depression, Environmental Reward, Coping Motives and Alcohol Consumption during the COVID-19 Pandemic</article-title>. <source>Front Psychiatry</source> (<year>2020</year>) <volume>11</volume>:<fpage>574676</fpage>. <pub-id pub-id-type="doi">10.3389/fpsyt.2020.574676</pub-id>
</citation>
</ref>
<ref id="B32">
<label>32.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Acuff</surname>
<given-names>SF</given-names>
</name>
<name>
<surname>Strickland</surname>
<given-names>JC</given-names>
</name>
<name>
<surname>Tucker</surname>
<given-names>JA</given-names>
</name>
<name>
<surname>Murphy</surname>
<given-names>JG</given-names>
</name>
</person-group>. <article-title>Changes in Alcohol Use during COVID-19 and Associations with Contextual and Individual Difference Variables: A Systematic Review and Meta-Analysis</article-title>. <source>Psychol Addict Behav</source> (<year>2022</year>) <volume>36</volume>(<issue>1</issue>):<fpage>1</fpage>&#x2013;<lpage>19</lpage>. <pub-id pub-id-type="doi">10.1037/adb0000796</pub-id>
</citation>
</ref>
<ref id="B33">
<label>33.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Garnett</surname>
<given-names>C</given-names>
</name>
<name>
<surname>Jackson</surname>
<given-names>S</given-names>
</name>
<name>
<surname>Oldham</surname>
<given-names>M</given-names>
</name>
<name>
<surname>Brown</surname>
<given-names>J</given-names>
</name>
<name>
<surname>Steptoe</surname>
<given-names>A</given-names>
</name>
<name>
<surname>Fancourt</surname>
<given-names>D</given-names>
</name>
</person-group>. <article-title>Factors Associated with Drinking Behaviour during COVID-19 Social Distancing and Lockdown Among Adults in the UK</article-title>. <source>Drug Alcohol Depend</source> (<year>2021</year>) <volume>219</volume>:<fpage>108461</fpage>. <pub-id pub-id-type="doi">10.1016/j.drugalcdep.2020.108461</pub-id>
</citation>
</ref>
<ref id="B34">
<label>34.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Kilian</surname>
<given-names>C</given-names>
</name>
<name>
<surname>Carr</surname>
<given-names>S</given-names>
</name>
<name>
<surname>Schulte</surname>
<given-names>B</given-names>
</name>
<name>
<surname>Manthey</surname>
<given-names>J</given-names>
</name>
</person-group>. <article-title>Increased Alcohol&#x2010;specific Mortality in Germany during COVID&#x2010;19: State&#x2010;level Trends from 2010 to 2020</article-title>. <source>Drug Alcohol Rev</source> (<year>2022</year>) <volume>42</volume>:<fpage>633</fpage>&#x2013;<lpage>40</lpage>. <pub-id pub-id-type="doi">10.1111/dar.13573</pub-id>
</citation>
</ref>
<ref id="B35">
<label>35.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Tucker</surname>
<given-names>JS</given-names>
</name>
<name>
<surname>Rodriguez</surname>
<given-names>A</given-names>
</name>
<name>
<surname>Green</surname>
<given-names>HD</given-names>
<suffix>Jr</suffix>
</name>
<name>
<surname>Pollard</surname>
<given-names>MS</given-names>
</name>
</person-group>. <article-title>Trajectories of Alcohol Use and Problems during the COVID-19 Pandemic: The Role of Social Stressors and Drinking Motives for Men and Women</article-title>. <source>Drug and Alcohol Dependence</source> (<year>2022</year>) <volume>232</volume>:<fpage>109285</fpage>. <pub-id pub-id-type="doi">10.1016/j.drugalcdep.2022.109285</pub-id>
</citation>
</ref>
<ref id="B36">
<label>36.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Patel</surname>
<given-names>AK</given-names>
</name>
<name>
<surname>Balasanova</surname>
<given-names>AA</given-names>
</name>
</person-group>. <article-title>Unhealthy Alcohol Use</article-title>. <source>JAMA</source> (<year>2021</year>) <volume>326</volume>(<issue>2</issue>):<fpage>196</fpage>. <pub-id pub-id-type="doi">10.1001/jama.2020.2015</pub-id>
</citation>
</ref>
<ref id="B37">
<label>37.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Rehm</surname>
<given-names>J</given-names>
</name>
</person-group>. <article-title>The Risks Associated with Alcohol Use and Alcoholism</article-title>. <source>Alcohol Res Health</source> (<year>2011</year>) <volume>34</volume>(<issue>6</issue>):<fpage>135</fpage>&#x2013;<lpage>43</lpage>.</citation>
</ref>
<ref id="B38">
<label>38.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Capasso</surname>
<given-names>A</given-names>
</name>
<name>
<surname>Jones</surname>
<given-names>AM</given-names>
</name>
<name>
<surname>Ali</surname>
<given-names>SH</given-names>
</name>
<name>
<surname>Foreman</surname>
<given-names>J</given-names>
</name>
<name>
<surname>Tozan</surname>
<given-names>Y</given-names>
</name>
<name>
<surname>DiClemente</surname>
<given-names>RJ</given-names>
</name>
</person-group>. <article-title>Increased Alcohol Use during the COVID-19 Pandemic: The Effect of Mental Health and Age in a Cross-Sectional Sample of Social media Users in the US</article-title>. <source>Prev Med</source> (<year>2021</year>) <volume>145</volume>:<fpage>106422</fpage>. <pub-id pub-id-type="doi">10.1016/j.ypmed.2021.106422</pub-id>
</citation>
</ref>
<ref id="B39">
<label>39.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Deeken</surname>
<given-names>F</given-names>
</name>
<name>
<surname>Reichert</surname>
<given-names>M</given-names>
</name>
<name>
<surname>Zech</surname>
<given-names>H</given-names>
</name>
<name>
<surname>Wenzel</surname>
<given-names>J</given-names>
</name>
<name>
<surname>Wedemeyer</surname>
<given-names>F</given-names>
</name>
<name>
<surname>Aguilera</surname>
<given-names>A</given-names>
</name>
<etal/>
</person-group> <article-title>Patterns of Alcohol Consumption Among Individuals with Alcohol Use Disorder during the COVID-19 Pandemic and Lockdowns in Germany</article-title>. <source>JAMA Netw Open</source> (<year>2022</year>) <volume>5</volume>(<issue>8</issue>):<fpage>e2224641</fpage>. <pub-id pub-id-type="doi">10.1001/jamanetworkopen.2022.24641</pub-id>
</citation>
</ref>
<ref id="B40">
<label>40.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Harris</surname>
<given-names>PA</given-names>
</name>
<name>
<surname>Taylor</surname>
<given-names>R</given-names>
</name>
<name>
<surname>Minor</surname>
<given-names>BL</given-names>
</name>
<name>
<surname>Elliott</surname>
<given-names>V</given-names>
</name>
<name>
<surname>Fernandez</surname>
<given-names>M</given-names>
</name>
<name>
<surname>O&#x27;Neal</surname>
<given-names>L</given-names>
</name>
<etal/>
</person-group> <article-title>The REDCap Consortium: Building an International Community of Software Platform Partners</article-title>. <source>J Biomed Inform</source> (<year>2019</year>) <volume>95</volume>:<fpage>103208</fpage>. <pub-id pub-id-type="doi">10.1016/j.jbi.2019.103208</pub-id>
</citation>
</ref>
<ref id="B41">
<label>41.</label>
<citation citation-type="book">
<person-group person-group-type="author">
<name>
<surname>Harkness</surname>
<given-names>A</given-names>
</name>
</person-group>. <source>The Pandemic Stress Index</source>. <publisher-loc>Coral Gables, FL</publisher-loc>: <publisher-name>University of Miami</publisher-name> (<year>2020</year>).</citation>
</ref>
<ref id="B42">
<label>42.</label>
<citation citation-type="book">
<person-group person-group-type="author">
<name>
<surname>Stoddard</surname>
<given-names>J</given-names>
</name>
<name>
<surname>Reynolds</surname>
<given-names>EK</given-names>
</name>
<name>
<surname>Paris</surname>
<given-names>R</given-names>
</name>
<name>
<surname>Haller</surname>
<given-names>S</given-names>
</name>
<name>
<surname>Johnson</surname>
<given-names>S</given-names>
</name>
<name>
<surname>Zik</surname>
<given-names>J</given-names>
</name>
<etal/>
</person-group> <source>The Coronavirus Impact Scale: Construction, Validation, and Comparisons in Diverse Clinical Samples</source>. <comment>PsyArXiv Preprints [Preprint]</comment> (<year>2021</year>). <comment>Available at: <ext-link ext-link-type="uri" xlink:href="https://psyarxiv.com/kz4pg/">https://psyarxiv.com/kz4pg/</ext-link>
</comment> (<comment>Accessed October 22, 2022</comment>).</citation>
</ref>
<ref id="B43">
<label>43.</label>
<citation citation-type="book">
<person-group person-group-type="author">
<name>
<surname>Mehta</surname>
<given-names>S</given-names>
</name>
</person-group>. <source>COVID-19 Community Response Survey</source>. <publisher-loc>Baltimore, Maryland</publisher-loc>: <publisher-name>Johns Hopkins Bloomberg School of Public Health</publisher-name> (<year>2020</year>). <comment>Available at: <ext-link ext-link-type="uri" xlink:href="https://tools.niehs.nih.gov/dr2/index.cfm/resource/22096">https://tools.niehs.nih.gov/dr2/index.cfm/resource/22096</ext-link>
</comment> (<comment>Accessed November 2, 2022</comment>).</citation>
</ref>
<ref id="B44">
<label>44.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Hamilton</surname>
<given-names>CM</given-names>
</name>
<name>
<surname>Strader</surname>
<given-names>LC</given-names>
</name>
<name>
<surname>Pratt</surname>
<given-names>JG</given-names>
</name>
<name>
<surname>Maiese</surname>
<given-names>D</given-names>
</name>
<name>
<surname>Hendershot</surname>
<given-names>T</given-names>
</name>
<name>
<surname>Kwok</surname>
<given-names>RK</given-names>
</name>
<etal/>
</person-group> <article-title>The PhenX Toolkit: Get the Most from Your Measures</article-title>. <source>Am J Epidemiol</source> (<year>2011</year>) <volume>174</volume>(<issue>3</issue>):<fpage>253</fpage>&#x2013;<lpage>60</lpage>. <pub-id pub-id-type="doi">10.1093/aje/kwr193</pub-id>
</citation>
</ref>
<ref id="B45">
<label>45.</label>
<citation citation-type="book">
<collab>SAS Institute Inc</collab>. <source>SAS/ACCESS 9.4 Interface to ADABAS: Reference</source>. <publisher-loc>Cary, NC</publisher-loc>: <publisher-name>SAS Institute Inc.</publisher-name> (<year>2013</year>).</citation>
</ref>
<ref id="B46">
<label>46.</label>
<citation citation-type="book">
<collab>StataCorp</collab>. <source>Stata Statistical Software: Release</source>, <volume>15</volume>. <publisher-loc>College Station, TX</publisher-loc>: <publisher-name>StataCorp LLC</publisher-name> (<year>2017</year>).</citation>
</ref>
<ref id="B47">
<label>47.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Galea</surname>
<given-names>S</given-names>
</name>
<name>
<surname>Merchant</surname>
<given-names>RM</given-names>
</name>
<name>
<surname>Lurie</surname>
<given-names>N</given-names>
</name>
</person-group>. <article-title>The Mental Health Consequences of COVID-19 and Physical Distancing: The Need for Prevention and Early Intervention</article-title>. <source>JAMA Inter Med</source> (<year>2020</year>) <volume>180</volume>(<issue>6</issue>):<fpage>817</fpage>&#x2013;<lpage>8</lpage>. <pub-id pub-id-type="doi">10.1001/jamainternmed.2020.1562</pub-id>
</citation>
</ref>
<ref id="B48">
<label>48.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Clay</surname>
<given-names>JM</given-names>
</name>
<name>
<surname>Parker</surname>
<given-names>MO</given-names>
</name>
</person-group>. <article-title>Alcohol Use and Misuse during the COVID-19 Pandemic: A Potential Public Health Crisis?</article-title> <source>Lancet Public Health</source> (<year>2020</year>) <volume>5</volume>(<issue>5</issue>):<fpage>e259</fpage>. <pub-id pub-id-type="doi">10.1016/S2468-2667(20)30088-8</pub-id>
</citation>
</ref>
<ref id="B49">
<label>49.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Kilian</surname>
<given-names>C</given-names>
</name>
<name>
<surname>O&#x27;Donnell</surname>
<given-names>A</given-names>
</name>
<name>
<surname>Potapova</surname>
<given-names>N</given-names>
</name>
<name>
<surname>L&#xf3;pez&#x2010;Pelayo</surname>
<given-names>H</given-names>
</name>
<name>
<surname>Schulte</surname>
<given-names>B</given-names>
</name>
<name>
<surname>Miquel</surname>
<given-names>L</given-names>
</name>
<etal/>
</person-group> <article-title>Changes in Alcohol Use during the COVID&#x2010;19 Pandemic in Europe: A Meta&#x2010;analysis of Observational Studies</article-title>. <source>Drug Alcohol Rev</source> (<year>2022</year>) <volume>41</volume>(<issue>4</issue>):<fpage>918</fpage>&#x2013;<lpage>31</lpage>. <pub-id pub-id-type="doi">10.1111/dar.13446</pub-id>
</citation>
</ref>
<ref id="B50">
<label>50.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Gritsenko</surname>
<given-names>V</given-names>
</name>
<name>
<surname>Skugarevsky</surname>
<given-names>O</given-names>
</name>
<name>
<surname>Konstantinov</surname>
<given-names>V</given-names>
</name>
<name>
<surname>Gritsenko</surname>
<given-names>V</given-names>
</name>
<name>
<surname>Skugarevsky</surname>
<given-names>O</given-names>
</name>
<name>
<surname>Konstantinov</surname>
<given-names>V</given-names>
</name>
<etal/>
</person-group> <article-title>COVID 19 Fear, Stress, Anxiety, and Substance Use Among Russian and Belarusian university Students</article-title>. <source>Int J Ment Health Addict</source> (<year>2020</year>) <volume>19</volume>:<fpage>2362</fpage>&#x2013;<lpage>8</lpage>. <pub-id pub-id-type="doi">10.1007/s11469-020-00330-z</pub-id>
</citation>
</ref>
<ref id="B51">
<label>51.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Lechner</surname>
<given-names>WV</given-names>
</name>
<name>
<surname>Laurene</surname>
<given-names>KR</given-names>
</name>
<name>
<surname>Patel</surname>
<given-names>S</given-names>
</name>
<name>
<surname>Anderson</surname>
<given-names>M</given-names>
</name>
<name>
<surname>Grega</surname>
<given-names>C</given-names>
</name>
<name>
<surname>Kenne</surname>
<given-names>DR</given-names>
</name>
</person-group>. <article-title>Changes in Alcohol Use as a Function of Psychological Distress and Social Support Following COVID-19 Related University Closings</article-title>. <source>Addict Behav</source> (<year>2020</year>) <volume>110</volume>:<fpage>106527</fpage>. <pub-id pub-id-type="doi">10.1016/j.addbeh.2020.106527</pub-id>
</citation>
</ref>
<ref id="B52">
<label>52.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Callinan</surname>
<given-names>S</given-names>
</name>
<name>
<surname>Smit</surname>
<given-names>K</given-names>
</name>
<name>
<surname>Mojica&#x2010;Perez</surname>
<given-names>Y</given-names>
</name>
<name>
<surname>D&#x27;Aquino</surname>
<given-names>S</given-names>
</name>
<name>
<surname>Moore</surname>
<given-names>D</given-names>
</name>
<name>
<surname>Kuntsche</surname>
<given-names>E</given-names>
</name>
</person-group>. <article-title>Shifts in Alcohol Consumption during the COVID&#x2010;19 Pandemic: Early Indications from Australia</article-title>. <source>Addiction</source> (<year>2021</year>) <volume>116</volume>(<issue>6</issue>):<fpage>1381</fpage>&#x2013;<lpage>8</lpage>. <pub-id pub-id-type="doi">10.1111/add.15275</pub-id>
</citation>
</ref>
<ref id="B53">
<label>53.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Rodriguez</surname>
<given-names>LM</given-names>
</name>
<name>
<surname>Litt</surname>
<given-names>DM</given-names>
</name>
<name>
<surname>Stewart</surname>
<given-names>SH</given-names>
</name>
</person-group>. <article-title>Drinking to Cope with the Pandemic: The Unique Associations of COVID-19-Related Perceived Threat and Psychological Distress to Drinking Behaviors in American Men and Women</article-title>. <source>Addict Behav</source> (<year>2020</year>) <volume>110</volume>:<fpage>106532</fpage>. <pub-id pub-id-type="doi">10.1016/j.addbeh.2020.106532</pub-id>
</citation>
</ref>
<ref id="B54">
<label>54.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Carlyle</surname>
<given-names>M</given-names>
</name>
<name>
<surname>Leung</surname>
<given-names>J</given-names>
</name>
<name>
<surname>Walter</surname>
<given-names>ZC</given-names>
</name>
<name>
<surname>Juckel</surname>
<given-names>J</given-names>
</name>
<name>
<surname>Salom</surname>
<given-names>C</given-names>
</name>
<name>
<surname>Quinn</surname>
<given-names>CA</given-names>
</name>
<etal/>
</person-group> <article-title>Changes in Substance Use Among People Seeking Alcohol and Other Drug Treatment during the COVID-19 Pandemic: Evaluating Mental Health Outcomes and Resilience</article-title>. <source>Subst Abuse</source> (<year>2021</year>) <volume>15</volume>:<fpage>11782218211061746</fpage>&#x2013;<lpage>8</lpage>. <pub-id pub-id-type="doi">10.1177/11782218211061746</pub-id>
</citation>
</ref>
<ref id="B55">
<label>55.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>De Goeij</surname>
<given-names>MC</given-names>
</name>
<name>
<surname>Suhrck</surname>
<given-names>M</given-names>
</name>
<name>
<surname>Toffolutti</surname>
<given-names>V</given-names>
</name>
<name>
<surname>van de Mheen</surname>
<given-names>D</given-names>
</name>
<name>
<surname>Schoenmakers</surname>
<given-names>TM</given-names>
</name>
<name>
<surname>Kunst</surname>
<given-names>AE</given-names>
</name>
</person-group>. <article-title>How Economic Crises Affect Alcohol Consumption and Alcohol-Related Health Problems: a Realist Systematic Review</article-title>. <source>Soc Sci Med</source> (<year>2015</year>) <volume>131</volume>:<fpage>131</fpage>&#x2013;<lpage>46</lpage>. <pub-id pub-id-type="doi">10.1016/j.socscimed.2015.02.025</pub-id>
</citation>
</ref>
<ref id="B56">
<label>56.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Nielsen</surname>
<given-names>MB</given-names>
</name>
<name>
<surname>Christensen</surname>
<given-names>JO</given-names>
</name>
<name>
<surname>Knardahl</surname>
<given-names>S</given-names>
</name>
</person-group>. <article-title>Working at home and Alcohol Use</article-title>. <source>Addict Behav Rep</source> (<year>2021</year>) <volume>14</volume>:<fpage>100377</fpage>. <pub-id pub-id-type="doi">10.1016/j.abrep.2021.100377</pub-id>
</citation>
</ref>
<ref id="B57">
<label>57.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Hanson</surname>
<given-names>JD</given-names>
</name>
<name>
<surname>Noonan</surname>
<given-names>C</given-names>
</name>
<name>
<surname>Harris</surname>
<given-names>A</given-names>
</name>
<name>
<surname>Oziel</surname>
<given-names>K</given-names>
</name>
<name>
<surname>Sarche</surname>
<given-names>M</given-names>
</name>
<name>
<surname>MacLehose</surname>
<given-names>RF</given-names>
</name>
<etal/>
</person-group> <article-title>Alcohol Consumption during COVID Among Women with an Existing Alcohol-Use Disorder</article-title>. <source>Int J Environ Res Public Health</source> (<year>2021</year>) <volume>18</volume>(<issue>18</issue>):<fpage>9460</fpage>. <pub-id pub-id-type="doi">10.3390/ijerph18189460</pub-id>
</citation>
</ref>
<ref id="B58">
<label>58.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Pollard</surname>
<given-names>MS</given-names>
</name>
<name>
<surname>Tucker</surname>
<given-names>JS</given-names>
</name>
<name>
<surname>Green</surname>
<given-names>HD</given-names>
</name>
</person-group>. <article-title>Changes in Adult Alcohol Use and Consequences during the COVID-19 Pandemic in the US</article-title>. <source>JAMA Netw Open</source> (<year>2020</year>) <volume>3</volume>(<issue>9</issue>):<fpage>e2022942</fpage>. <pub-id pub-id-type="doi">10.1001/jamanetworkopen.2020.22942</pub-id>
</citation>
</ref>
<ref id="B59">
<label>59.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Avena</surname>
<given-names>NM</given-names>
</name>
<name>
<surname>Simkus</surname>
<given-names>J</given-names>
</name>
<name>
<surname>Lewandowski</surname>
<given-names>A</given-names>
</name>
<name>
<surname>Gold</surname>
<given-names>MS</given-names>
</name>
<name>
<surname>Potenza</surname>
<given-names>MN</given-names>
</name>
</person-group>. <article-title>Substance Use Disorders and Behavioral Addictions during the COVID-19 Pandemic and COVID-19-Related Restrictions</article-title>. <source>Front Psychiatry</source> (<year>2021</year>) <volume>12</volume>:<fpage>653674</fpage>. <pub-id pub-id-type="doi">10.3389/fpsyt.2021.653674</pub-id>
</citation>
</ref>
<ref id="B60">
<label>60.</label>
<citation citation-type="web">
<person-group person-group-type="author">
<name>
<surname>TheCorporation</surname>
<given-names>RAND</given-names>
</name>
</person-group>. <article-title>Alcohol Consumption Rises Sharply during Pandemic Shutdown; Heavy Drinking by Women Rises 41%</article-title> (<year>2020</year>). <comment>Available at: <ext-link ext-link-type="uri" xlink:href="https://www.rand.org/news/press/2020/09/29.html">https://www.rand.org/news/press/2020/09/29.html</ext-link> (Accessed December 1, 2022)</comment>.</citation>
</ref>
<ref id="B61">
<label>61.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Peltier</surname>
<given-names>MR</given-names>
</name>
<name>
<surname>Verplaetse</surname>
<given-names>TL</given-names>
</name>
<name>
<surname>Mineur</surname>
<given-names>YS</given-names>
</name>
<name>
<surname>Petrakis</surname>
<given-names>IL</given-names>
</name>
<name>
<surname>Cosgrove</surname>
<given-names>KP</given-names>
</name>
<name>
<surname>Picciotto</surname>
<given-names>MR</given-names>
</name>
<etal/>
</person-group> <article-title>Sex Differences in Stress-Related Alcohol Use</article-title>. <source>Neurobiol Stress</source> (<year>2019</year>) <volume>10</volume>:<fpage>100149</fpage>. <pub-id pub-id-type="doi">10.1016/j.ynstr.2019.100149</pub-id>
</citation>
</ref>
<ref id="B62">
<label>62.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Morens</surname>
<given-names>DM</given-names>
</name>
<name>
<surname>Fauci</surname>
<given-names>AS</given-names>
</name>
</person-group>. <article-title>Emerging Pandemic Diseases: How We Got to COVID-19</article-title>. <source>Cell</source> (<year>2020</year>) <volume>182</volume>(<issue>5</issue>):<fpage>1077</fpage>&#x2013;<lpage>92</lpage>. <pub-id pub-id-type="doi">10.1016/j.cell.2020.08.021</pub-id>
</citation>
</ref>
<ref id="B63">
<label>63.</label>
<citation citation-type="book">
<person-group person-group-type="author">
<name>
<surname>Dey</surname>
<given-names>M</given-names>
</name>
<name>
<surname>Frazis</surname>
<given-names>H</given-names>
</name>
<name>
<surname>Loewenstein</surname>
<given-names>MA</given-names>
</name>
<name>
<surname>Sun</surname>
<given-names>H</given-names>
</name>
</person-group>. <source>Ability to Work from home: Evidence from Two Surveys and Implications for the Labor Market in the COVID-19 Pandemic</source>. <publisher-loc>Washington, D.C., US</publisher-loc>: <publisher-name>Monthly Labor Review U.S. Bureau of Labor Statistics</publisher-name> (<year>2020</year>). <pub-id pub-id-type="doi">10.21916/mlr.2020.14</pub-id>
</citation>
</ref>
<ref id="B64">
<label>64.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Jeremy</surname>
<given-names>N</given-names>
</name>
<name>
<surname>Michael</surname>
<given-names>L</given-names>
</name>
</person-group>. <article-title>Accuracy of Self-Reported Drinking: Observational Verification of &#x2018;Last Occasion&#x2019; Drink Estimates of Young Adults</article-title>. <source>Alcohol Alcohol</source> (<year>2011</year>) <volume>46</volume>(<issue>6</issue>):<fpage>709</fpage>&#x2013;<lpage>13</lpage>. <pub-id pub-id-type="doi">10.1093/alcalc/agr138</pub-id>
</citation>
</ref>
</ref-list>
</back>
</article>