AUTHOR=Iten Fabian , Weiss Julius , Schwab Simon , Beyeler Franziska , Krueger Thorsten , Koutsokera Angela , Schuurmans Macé , Opitz Isabelle , Lang György , Immer Franz 
  
TITLE=Association Between Three Lung Donor Scores and Lung Acceptance in DBD and DCD Donors
  
JOURNAL=Transplant International
  
VOLUME=Volume 39 - 2026
  
YEAR=2026
  
URL=https://www.frontierspartnerships.org/journals/transplant-international/articles/10.3389/ti.2026.15901
  
DOI=10.3389/ti.2026.15901
  
ISSN=1432-2277
  
ABSTRACT=The use of extended criteria donors (ECD) has become increasingly important in lung transplantation to address organ donor shortages. To better assess lung graft quality and optimize donor selection, several scores have been developed. This study assesses whether Swiss lung acceptance practice is associated with three validated lung donor scores — the Oto Score, Eurotransplant Score (ET), and Zurich Donor Score (ZDS) — in both DBD and DCD donors. Due to limited clinical data, certain parameters of the Oto and ET Scores were adapted (aOto and aET). Data from 1515 actual deceased donors between 01.07.2014 and 30.06.2024 were analyzed. Logistic regression and AUC-ROC analysis were used to evaluate the scores' discriminative ability. Results showed that all three scores were associated with lung acceptance, with AUC values indicating acceptable to moderate discriminative ability — 0.75 for aOto, 0.70 for aET, and 0.77 for ZDS — and DCD donors being consistently less likely to be accepted for lung transplantation compared to DBD donors. Nonetheless, all three scores showed limitations as standalone models. Developing a novel, nationally applicable Swiss prediction tool integrating current lung acceptance criteria and recipient factors could improve donor–recipient matching, support more efficient organ utilization, and potentially increase transplant activity.